Related Experiment Video
Updated: Aug 24, 2026
A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes
Published on: October 28, 2021
[Antioxidant system of the rat brain in toxic lung edema]
N N Pluzhnikov1, A A Tiaptin, A V Zemlianoĭ
1Research Center of Biological Defence, Institute of Military Medicine, Defence Ministry, St. Petersburg, 195043, Russia.
Abstract:
The state of enzymatic and nonenzymatic components of antioxidant system and also lipid peroxidation processes were studied in brain of rats with toxic pulmonary edema induced by inhalation of nitric oxides. The changes in the state of antioxidant system components in brain accompanied the development of toxic pulmonary edema. The main changes were found in nonenzymatic components of the antioxidant system, particularly in thiol and disulfide groups. Lipid peroxidation processes were not activated during the toxic pulmonary edema.
