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Published on: October 20, 2017
Angioplasty or stenting of extra- and intracranial vertebral artery stenoses
Elke A M Hauth1, H Martin Gissler, Robert Drescher
1Department of Radiology and Interventional Radiology, University Hospital Essen, Essen, Germany.
Insights
Angioplasty and stenting of vertebral artery (VA) stenosis is feasible and safe for extracranial cases. Intracranial VA stenosis procedures are possible but carry life-threatening risks, requiring further study.
Area of Science:
- Vascular Surgery
- Interventional Neuroradiology
- Cardiovascular Medicine
Background:
- Vertebral artery (VA) stenosis poses a risk of stroke.
- Treatment options for VA stenosis include angioplasty and stenting.
Purpose of the Study:
- To evaluate the feasibility and safety of angioplasty or angioplasty and stenting for extra- and intracranial vertebral artery stenosis.
Main Methods:
- 16 patients with 16 stenotic VAs underwent angioplasty or angioplasty with stenting.
- Stenoses were located in V1, V2, and V4 segments; 14 were symptomatic and atherosclerotic.
Main Results:
- Procedures were technically successful in 14 of 16 VAs (87%).
- Complications included asymptomatic vessel dissection and one fatal subarachnoid hemorrhage due to vessel perforation.
Conclusions:
- Extracranial VA stenosis treatment with angioplasty/stenting shows high success and low complication rates.
- Intracranial VA stenosis procedures are feasible but associated with potentially life-threatening complications.
- Future research should focus on durability and complication rates of primary stenting without predilation.
Purpose:
To determine the feasibility and safety of angioplasty or angioplasty and stenting of extra- and intracranial vertebral artery (VA) stenosis.
Methods:
In 16 consecutive patients (9 men, 7 women; mean age 61 years, range 49-74 years) 16 stenotic VAs were treated with angioplasty or angioplasty and stenting. Eleven stenoses were localized in V1 segment, 1 stenosis in V2 segment and 4 stenoses in V4 segment of VA. Fourteen VA stenoses were symptomatic, 2 asymptomatic. The etiology of the stenoses was atherosclerotic in all cases.
Results:
Angioplasty was performed in 8 of 11 V1 and 2 of 4 V4 segments of the VA. In 3 of 11 V1 segments and 2 of 4 V4 segments of the VA we combined angioplasty with stenting. The procedures were successfully performed in 14 of 16 VAs (87%). Complications were asymptomatic vessel dissection resulting in vessel occlusion in 1 of 11 V1 segments and asymptomatic vessel dissection in 2 of 4 V4 segments of the VA. One patient died in the 24-hr period after the procedure because of subarachnoid hemorrhage as a complication following vessel perforation of the treated V4 segment.
Conclusion:
Angioplasty or angioplasty and stenting of extracranial VA stenoses can be performed with a high technical success rate and a low complication rate. In intracranial VA stenosis the procedure is technically feasible but complications can be life-threatening. The durability and procedural complication rates of primary stenting without using predilation in extra- and intracranial VA stenosis should be defined in the future.
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