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Related Experiment Videos

Tidal peritoneal dialysis: preliminary experience.

M J Flanigan1, C Doyle, V S Lim

  • 1Department of Medicine, University of Iowa Hospitals and Clinics, Iowa City 52240.

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|January 1, 1992
PubMed
Summary
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Home tidal peritoneal dialysis (TPD) offers comparable uremia control to continuous cycling peritoneal dialysis (CCPD) in just eight hours. This pilot study demonstrates TPD feasibility for patients seeking reduced dialysis time.

Area of Science:

  • Nephrology
  • Renal Replacement Therapy
  • Dialysis Technology

Background:

  • Continuous cycling peritoneal dialysis (CCPD) is a common treatment for end-stage renal disease.
  • Patients may seek alternative dialysis modalities to reduce treatment time or improve convenience.
  • Home-based dialysis offers potential benefits for patient autonomy and quality of life.

Purpose of the Study:

  • To evaluate the feasibility of home tidal peritoneal dialysis (TPD).
  • To compare the efficacy of eight-hour TPD with CCPD in achieving uremia control and urea removal.
  • To assess patient acceptance of TPD for home use.

Main Methods:

  • An open enrollment pilot study was conducted at a tertiary care teaching hospital.
  • Nine experienced CCPD patients living remotely initiated TPD, aiming for reduced dialysis duration.

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  • Prescriptions were adjusted every 4-6 weeks to match CCPD's urea removal, with dialysate analysis and patient interviews informing adjustments.

    • Main Results:

    • Eight hours of TPD, with specific fill and tidal volumes, achieved urea removal equivalent to the patients' prior CCPD regimen.
    • Urea and creatinine clearances correlated positively with dialysate flow rates.
    • Dialysate nonurea nitrogen levels remained stable despite variations in dialysate volume.

    Conclusions:

    • Home TPD is a feasible alternative to CCPD, offering equivalent uremia control in a shorter treatment duration.
    • TPD requires a larger dialysate volume compared to CCPD (16.0 L vs 9.5 L).
    • TPD may be a viable option for patients desiring reduced dialysis time while maintaining treatment efficacy.