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Decreased serum homocysteine in pregnancy
A Andersson1, B Hultberg, L Brattström
1Department of Clinical Chemistry, University Hospital, Lund, Sweden.
Abstract:
Total serum homocysteine was found to be significantly decreased in the first trimester of pregnancy, became maximal in the second trimester (about 50% compared with non-pregnant women), whereafter the concentration remained stable throughout the remainder of pregnancy. A return to normal concentrations was seen within 2-4 days post partum. Possible reasons for the decrease of serum homocysteine in pregnancy could be haemodilution and increased remethylation of homocysteine due to increased demands for methionine by the foetus.
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