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Lacrimostimulants and lacrimomimetics
1Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4, Canada. bruce.grahn@usask.ca
Summary
Veterinarians can better diagnose and treat tear film abnormalities by understanding tear film physiology. This review covers tear film anatomy, physiology, and therapeutic options like lacrimostimulants and lacrimomimetics.
Area of Science:
- Veterinary ophthalmology
- Ocular surface disease
Background:
- Tear film abnormalities are common in veterinary medicine.
- Accurate diagnosis and treatment require understanding tear film physiology.
- Quantitative and qualitative deficiencies impact ocular health.
Purpose of the Study:
- To provide a comprehensive review of tear film physiology and abnormalities.
- To guide veterinarians in diagnosing and treating tear film deficiencies.
- To discuss lacrimostimulatory and lacrimomimetic therapies.
Main Methods:
- Review of embryology, anatomy, and physiology of ocular glands.
- Discussion of the pathophysiology of tear film deficiencies.
- Overview of pharmacological agents for tear film disorders.
Main Results:
- Detailed explanation of the components of the tear film.
- Pathophysiology of decreased aqueous, mucin, and lipid layers.
- Identification of key therapeutic agents.
Conclusions:
- Understanding tear film physiology is crucial for veterinary diagnosis and treatment.
- Various lacrimostimulants and lacrimomimetics offer therapeutic options.
- Effective management of tear film abnormalities improves ocular health.