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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
[Modern diagnosis and treatment of heart failure]
Lars Gullestad1, Steinar Madsen
1Medisinsk avdeling, Sykehuset Asker og Baerum, Postboks 83, 1309 Rud. lars.gullestad@broadpark.no
Insights
Chronic heart failure (CHF) is a serious condition with poor outcomes. Effective treatments aim to slow disease progression and improve patient survival and quality of life.
Area of Science:
- Cardiology
- Internal Medicine
Context:
- Chronic heart failure (CHF) is a widespread condition with significant morbidity, mortality, and reduced quality of life.
- CHF represents the advanced stage of diverse heart diseases, carrying a prognosis poorer than many cancers.
Purpose:
- To outline the diagnostic criteria and current therapeutic strategies for chronic heart failure.
- To emphasize the goals of CHF management, focusing on disease progression and patient outcomes.
Summary:
- Diagnosis involves identifying characteristic symptoms and signs alongside objective evidence of cardiac dysfunction.
- Pharmacological treatments, primarily ACE inhibitors and beta-blockers, form the cornerstone of therapy.
- Non-pharmacological interventions are also utilized, with additional medications prescribed based on individual patient needs.
Impact:
- Improved understanding of CHF diagnosis and management.
- Potential for enhanced patient outcomes through optimized treatment strategies.
- Reduced healthcare burden associated with chronic heart failure.
Abstract:
Chronic heart failure is a prevalent condition associated with high morbidity, high mortality and reduced quality of life. Chronic heart failure is the end-stage of various forms of heart disease. The prognosis is poor, worse than for patients with various forms of cancer. The diagnosis of heart failure is made in the presence of multiple symptoms and signs combined with objective evidence of cardiac dysfunction. Treatment consists of pharmacological as well as non-pharmacological approaches. ACE inhibitors and beta-blockers are the basis of treatment, while diuretics and other medications are given on an individual basis. The aim of treatment is to reduce progression of the underlying disease and to reduce mortality and morbidity.
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