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Prophylactic migraine therapy: emerging treatment options
Marcelo E Bigal1, Abouch V Krymchantowski, Alan M Rapoport
1Department of Neurology, Albert Einstein College of Medicine, 1165 Morris Park Avenue, Bronx, NY 10461, USA. mbigal@aecom.yu.edu
Current Pain and Headache Reports
|April 30, 2004
Summary
This review covers new migraine prevention treatments, including medications like topiramate and botulinum toxin. It discusses current uses and emerging options for effective migraine management.
Area of Science:
- Neurology
- Pharmacology
Background:
- Migraine is a common neurological disorder with significant impact.
- Effective preventive strategies are crucial for managing chronic migraine.
Purpose of the Study:
- To review current and emerging treatment options for migraine prevention.
- To provide an overview of migraine pathophysiology and indications for preventive therapy.
Main Methods:
- Literature review of new and upcoming preventive medications for migraine.
- Discussion of data on specific agents including topiramate, levetiracetam, and others.
Main Results:
- Several pharmacological agents (e.g., topiramate, levetiracetam, zonisamide) are discussed for migraine prevention.
- Non-pharmacological options (e.g., botulinum toxin, Petasites, Coenzyme Q) are also reviewed.
- Current indications and emerging treatments are highlighted.
Conclusions:
- A range of new and established treatments are available for migraine prevention.
- Understanding pathophysiology aids in selecting appropriate preventive therapies.
- Ongoing research promises further advancements in migraine management.