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Updated: Aug 24, 2026

Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease with Fibrosis
Published on: July 18, 2025
Hypertransaminasemia and severe hepatic steatosis without inflammation. A case report
Nahum Méndez-Sánchez1, Daniel Motola-Kuba, Jesús Bahena-Aponte
1Department of Biomedical Research, Medica Sur Clinic & Foundation, Mexico City, Mexico. nmendez@medicasur.org.mx
Abstract:
Nonalcoholic fatty liver disease (NAFLD) is a medical condition that may progress to end-stage liver disease. The spectrum of NAFLD is wide and ranges from simple fat accumulation in hepatocytes (steatosis), to fat accumulation plus necroinflammatory activity with or without fibrosis (steatohepatitis). In addition, NAFLD is the most common cause of abnormal liver-test results among adults with a prevalence of 13%-23%. This case report is an example of a patient with asymptomatic hypertransaminasemia and severe hepatic steatosis without inflammation in which the diagnosis was made by liver biopsy.
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