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[The global cardiovascular risk chart].

Simona Giampaoli1, Luigi Palmieri, Paolo Chiodini

  • 1Centro Nazionale di Epidemiologia, Sorveglianza e Promozione della Salute, Istituto Superiore di Sanità, Roma. sgiamp@iss.it

Italian Heart Journal. Supplement : Official Journal of the Italian Federation of Cardiology
|May 1, 2004
PubMed
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The CUORE Project developed cardiovascular risk charts using Italian cohort data from the 1980s-1990s. These charts help identify individuals at high risk for cardiovascular disease, aiding clinical decision-making.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Context:

  • Longitudinal studies are crucial for developing risk functions to identify individuals at high risk for cardiovascular disease.
  • The CUORE Project utilized Italian cohort data from the 1980s and 1990s, collected through standardized procedures, to create global cardiovascular risk charts.
  • These charts are essential tools for risk stratification in cardiovascular disease prevention.

Purpose:

  • To develop and validate a global cardiovascular risk chart for the Italian population.
  • To identify key risk factors including age, gender, blood pressure, serum cholesterol, smoking, and diabetes.
  • To provide a practical tool for healthcare professionals to assess cardiovascular risk.

Summary:

  • The study analyzed data from 18,028 individuals aged 40-69 without prior cardiovascular events.

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  • 647 major cardiovascular events (449 coronary, 198 cerebrovascular) were identified over a median follow-up of 10 years for men and 5 years for women.
  • The resulting risk charts are stratified by gender and diabetes status, using color-coded risk levels for 10-year event probability.

    • Impact:

    • The developed risk charts offer a straightforward method for general practitioners and cardiologists to perform rapid and objective global cardiovascular risk evaluations.
    • Facilitates early identification of high-risk individuals, enabling timely intervention and personalized prevention strategies.
    • Contributes to the advancement of cardiovascular disease risk assessment tools in clinical practice.