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Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors
Published on: July 16, 2012
Interaction between HIV-1 and HCV infections: towards a new entity?
Maria Winnock1, Dominique Salmon-Céron, François Dabis
1INSERM U593, Université Victor Ségalen, 146 rue Léo Saignat, 33076 Bordeaux, France. Maria.Winnock@isped.u-bordeaux2.fr
Abstract:
Since human immunodeficiency virus (HIV) and hepatitis C virus (HCV) share the same modes of transmission, HIV-HCV co-infected patients are relatively common. Until recently, the clinical course of HCV in co-infected patients was overshadowed by the high morbidity and mortality of HIV disease. Recent reductions in morbidity and mortality among HIV-infected patients due to the advent of highly active antiretroviral therapy (HAART), have contributed to the emergence of HCV as a significant viral pathogen in this population. This article reviews the current evidence on the epidemiology and clinical implications of an interaction between HIV-1 and HCV infections.
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