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An empirical treatment algorithm for incontinent children.
Arne-Daniela Marschall-Kehrel1, Gerd Mürtz, Guus Kramer
1Urology Consultancy, Oberursel, Apogepha Arzneimittel GmbH, Dresden, Germany. kehrel.daniela@t-online.de
The Journal of Urology
|May 1, 2004
Summary
Propiverine monotherapy is effective for treating urge incontinence in children. Adjuvant therapies significantly increase continence rates in partial responders, reducing the need for specialized management.
Area of Science:
- Pediatric Urology
- Continence Management
Background:
- Monotherapy for pediatric urge incontinence has limited success rates.
- Adjuvant treatment strategies may improve outcomes in children with incontinence.
Purpose of the Study:
- To evaluate the efficacy of adjuvant treatment in children with urge incontinence.
- To assess if adjuvant therapies improve continence and functional bladder capacity.
Main Methods:
- Children with incontinence received propiverine (0.4 mg/kg) twice daily for 4 weeks.
- Partial responders underwent a second treatment period of 12 weeks with adjuvant therapies.
- Adjuvant treatments included alpha-blockers, desmopressin, or biofeedback.
Main Results:
- 29 out of 70 children achieved continence with initial propiverine therapy.
- 35 partial responders received adjuvant treatment, with 20 achieving continence.
- Overall efficacy was enhanced by combining propiverine with adjuvant modalities.
Conclusions:
- Propiverine monotherapy is an effective treatment for pediatric urge incontinence.
- Adjuvant treatment significantly improves overall efficacy in partial responders.
- This combined approach reduces the need for specialized management in children.