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Updated: Aug 24, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Age-related macular degeneration and depression: a review of recent research
Robin J Casten1, Barry W Rovner, William Tasman
1Jefferson Medical College and Wills Eye Hospital, and Jefferson Hospital for Neuroscience, 900 Walnut Street, 8th floor, Philadelphia, PA 19107, USA. Robin.Casten@Jefferson.edu
Purpose Of Review:
The purpose of this review is to summarize current research findings regarding relationships between depression and age-related macular degeneration (AMD).
Recent Findings:
The current literature indicates that the prevalence of depression among patients with AMD is fairly high (approximately 30%) and that depression is a major cause of disability among patients with AMD, even when severity of vision loss is considered. Interventions to alleviate the emotional distress associated with vision loss are also discussed.
Summary:
Several studies indicate that AMD is a risk factor for depression, and this has serious consequences for the quality of life among patients with AMD.
