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The effects of indomethacin on fibroblast chemotaxis
G W Kalmus1, J E Poulos, C W O'Rear
1Department of Biology, East Carolina University, Greenville, NC 27858-4353.
General Pharmacology
|May 1, 1992
Abstract:
1. Boyden chambers were used to investigate the effects of indomethacin on fibroblast chemotaxis to a conditioned medium. 2. It was determined that indomethacin did not inhibit, but enhanced fibroblast chemotaxis at a concentration of 10(-4) (91%)-10(-6) M (79%). 3. No significant difference was found between controls and cells treated with 10(-8)-10(-10) M indomethacin.