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Related Experiment Videos

[Acute therapy for eye burns].

N F Schrage1, R Rihawi, M Frentz

  • 1Universitätsaugenklinik Aachen. schrage@acto.de

Klinische Monatsblatter Fur Augenheilkunde
|May 1, 2004
PubMed
Summary

Buffered solutions with high buffering capacity are recommended for initial eye rinsing after chemical eye irritation. Osmolarity is a critical factor for future rinsing solutions, as water and saline are insufficient.

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[Recommendations for acute treatment for chemical and thermal burns of eyes and lids].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2011

Area of Science:

  • Ophthalmology
  • Toxicology
  • Biochemistry

Context:

  • Eye rinsing is crucial for treating chemical and thermal eye irritation.
  • Previous research focused on chemical neutralization, but new biological and chemical insights offer improved interventions.

Purpose:

  • To investigate the efficacy of different eye rinsing solutions based on osmolarity, buffering capacity, and solubility.
  • To evaluate new therapeutic mechanisms for eye rinsing after ocular irritation.

Summary:

  • Water and saline are ineffective buffers for eye burns; phosphate buffer shows weak buffering for alkali burns.
  • Diphoterine demonstrates high neutralization capacity for both alkali and acid burns.
  • Rinsing solution osmolarity and ionic content significantly impact corneal ion composition and osmolarity, with hyposmolar solutions potentially enhancing cellular damage.

Impact:

  • Recommends buffered solutions with high buffering capacity for initial eye rinsing.
  • Highlights osmolarity as a key factor for future eye rinsing solutions.
  • Suggests a shift from simple water rinsing to more advanced, targeted solutions for better ocular burn prognosis.

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