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Glutaraldehyde in bonding systems disinfects dentin in vitro
Patrick R Schmidlin1, Matthias Zehnder, Till N Göhring
1Department of Preventive Dentistry, Cariology, and Periodontology, University of Zürich Center for Dental Medicine, Zürich, Switzerland. patrick.schmidlin@zzmk.unizh.ch
The Journal of Adhesive Dentistry
|May 4, 2004
Summary
Glutaraldehyde-containing bonding agents effectively disinfect dentin against Enterococcus faecalis. This antibacterial action, observed even at low concentrations, supports their use in dental adhesive systems.
Area of Science:
- Dental materials science
- Microbiology
- Endodontics
Background:
- Dental caries and endodontic infections often involve bacterial contamination of dentin.
- Effective disinfection of dentin is crucial for successful dental restorative procedures.
- Glutaraldehyde is known for its antimicrobial properties.
Purpose of the Study:
- To evaluate the dentin disinfecting capacity of bonding agents containing glutaraldehyde.
- To assess the efficacy of specific bonding agents and their components against Enterococcus faecalis.
- To determine the antimicrobial activity of glutaraldehyde against E. faecalis.
Main Methods:
- Bovine dentin blocks infected with Enterococcus faecalis were treated with Syntac Classic bonding system, its components, or Gluma Primer.
- Bacterial growth was assessed from dentinal filings at various depths post-application.
- Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of glutaraldehyde were determined.
Main Results:
- Gluma Primer and Syntac Adhesive demonstrated significant dentin disinfection.
- Other components of the bonding system did not exhibit substantial antibacterial effects.
- The Syntac bonding system effectively disinfected dentin, irrespective of prior Gluma Primer application.
Conclusions:
- Bonding agents containing glutaraldehyde show promise as effective dentin disinfectants.
- These agents appear compatible with existing dental bonding systems.
- Further research is needed to clarify the effects of glutaraldehyde-containing agents on pulp tissue.