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Updated: Aug 24, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Melanin pigmented oncocytic metaplasia of the nasopharynx
Ken-ichi Takano1, Jun Sato, Hideaki Shirasaki
1Department of Otolaryngology, Sapporo Medical University School of Medicine, Chuou-ku, Sapporo 060-8556, Japan. kent@sapmed.ac.jp
Abstract:
A case of melanin pigmented oncocytic metaplasia is reported. A 62-year-old man presented with a history of discomfort of the ear of a 2 weeks' duration. Nasoscopic examination revealed a black nodule of about 5mm at the left Eustachian opening, and several black spots were discovered around the bilateral torus tubarius. The nodule was biopsied to determine the histology. Microscopically, there were oncocytic cells with abundant pigmented granules showing glandular pattern. Such a pigmented variant of benign oncocytic lesion is very rare.
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