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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
Published on: August 14, 2019
Insights
Annual influenza immunization is crucial for children, including healthy ones under 24 months, due to high hospitalization rates. This ensures protection against severe influenza complications and informs about updated vaccine recommendations.
Area of Science:
- Pediatric Infectious Diseases
- Vaccinology
- Public Health
Background:
- Children under 24 months and those with chronic conditions face high hospitalization rates for influenza, comparable to the elderly.
- Annual influenza immunization is recommended for high-risk children aged 6 months and older.
- Healthy young children are also at significant risk for influenza-related hospitalizations.
Framework:
- The American Academy of Pediatrics recommends influenza immunization for healthy children aged 6-24 months.
- Recommendations extend to household contacts, caregivers, and healthcare professionals for children under 24 months.
- Focus on identifying high-risk children and timely parental notification for annual immunization.
Implementation:
- Updating recommendations for the routine use of influenza vaccines in pediatric populations.
- Reviewing indications for both trivalent inactivated influenza vaccine (TIV) and live-attenuated influenza vaccine (LAIV).
Implications:
- Enhanced efforts are needed to ensure comprehensive protection against influenza complications in children.
- Improved identification and communication strategies are vital for maximizing vaccine uptake in at-risk pediatric groups.
- This statement aims to guide clinicians and public health officials on current influenza vaccination strategies for children.
Abstract:
Epidemiologic studies indicate that children of all ages with certain chronic conditions and otherwise healthy children younger than 24 months of age are hospitalized for influenza infection and its complications at high rates similar to those experienced by the elderly. Annual influenza immunization is recommended for all children with high-risk conditions who are 6 months of age and older. Young, healthy children are at high risk of hospitalization for influenza infection; therefore, the American Academy of Pediatrics recommends influenza immunization for healthy children 6 through 24 months of age, for household contacts and out-of-home caregivers of all children younger than 24 months of age, and for health care professionals. To protect these children more fully against the complications of influenza, increased efforts are needed to identify all high-risk children and inform their parents when annual immunization is due. The purposes of this statement are to update recommendations for routine use of influenza vaccine in children and to review the indications for use of trivalent inactivated influenza vaccine and live-attenuated influenza vaccine.
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