Duplicate genes increase gene expression diversity within and between species
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Updated: Aug 24, 2026

A Reverse Genetic Approach to Test Functional Redundancy During Embryogenesis
Published on: August 11, 2010
Zhenglong Gu1, Scott A Rifkin, Kevin P White
1Department of Ecology & Evolution, University of Chicago, 1101 East 57th Street, Chicago, Illinois 60637, USA.
Abstract:
Using microarray gene expression data from several Drosophila species and strains, we show that duplicated genes, compared with single-copy genes, significantly increase gene expression diversity during development. We show further that duplicate genes tend to cause expression divergences between Drosophila species (or strains) to evolve faster than do single-copy genes. This conclusion is also supported by data from different yeast strains.
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