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[Use of antimicrobial drugs in an urban population]
Laura S Berquó1, Aluísio J D Barros, Rosângela C Lima
1Programa de Pós-graduação em Epidemiologia, Faculdade de Medicina, Universidade Federal de Pelotas, Pelotas, RS, Brasil.
Objective:
The emergence of multiresistant microorganisms has been a concerning matter worldwide in the last decades. Indiscriminate use of antibiotics has been associated to this phenomenon. The present study was designed to determine the pattern of antimicrobial drug use in an urban community.
Methods:
A population-based cross-sectional study was carried out and 6,145 subjects of all ages living in the urban area of Pelotas, Brazil, were interviewed on the use of antimicrobial drugs in the 30 days previous to the interview.
Results:
The overall prevalence of antimicrobial drug use was 8%. It was higher for children under 4 years of age (14%; p<0.001), women (9%; p=0.004) and divorced subjects (10%; p=0.02). The clinical conditions most frequently associated with antimicrobial drug use were respiratory tract infections (50%), urinary tract infections (16%), and dental infections (9%). Penicillins (41%), sulphas (17%), and tetracycline (8%) were the most commonly used drugs.
Conclusions:
Abuse of last generation antimicrobial drugs, a concern of many experts, was not confirmed in this study. Antimicrobial drug use could be further reduced as respiratory illnesses, most frequently associated with their use, are often viral and many patients will not benefit from antimicrobial therapy.
Insights
Antimicrobial drug use was 8% in an urban Brazilian community, higher in young children and women. Most prescriptions were for respiratory infections, with penicillins being the most common drug.
Area of Science:
- Microbiology and Infectious Diseases
- Public Health
- Pharmacology
Context:
- Rising global concern over multiresistant microorganisms linked to antibiotic overuse.
- Need to understand antimicrobial drug consumption patterns in diverse populations.
- Previous studies highlight the association between antibiotic misuse and antimicrobial resistance.
Purpose:
- To investigate the prevalence and patterns of antimicrobial drug usage in an urban community in Pelotas, Brazil.
- To identify demographic groups with higher antimicrobial drug consumption.
- To determine the primary clinical indications and drug classes involved in antimicrobial use.
Summary:
- A cross-sectional study surveyed 6,145 individuals on their antimicrobial drug use in the past 30 days.
- Overall prevalence of antimicrobial drug use was 8%, with higher rates in children under 4 (14%) and women (9%).
- Respiratory tract infections (50%) were the leading indication, followed by urinary tract infections (16%); penicillins (41%) were the most frequently prescribed drugs.
Impact:
- Findings indicate a need for targeted interventions to optimize antimicrobial prescribing, particularly for respiratory conditions.
- Highlights the importance of public health strategies to reduce unnecessary antimicrobial use and combat resistance.
- Suggests potential for reducing antimicrobial consumption by addressing viral respiratory infections where antibiotics offer no benefit.
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