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Cerebral infarct in children aged zero to fifteen years

Thelma Ribeiro Noce1, Soraia Ramos Cabete Fábio, José Ibiapina Siqueira Neto

  • 1Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirao Preto, SP, Brazil.

Arquivos De Neuro-Psiquiatria
|May 4, 2004
PubMed

Insights

Cerebral infarcts in children often have unknown causes. Dehydration and septic shock were the most common identified causes in a Brazilian study, highlighting the need for preventive health measures.

Area of Science:

  • Pediatrics
  • Neurology
  • Stroke Research

Background:

  • Cerebral infarcts in children exhibit unique characteristics due to diverse or unknown etiologies.
  • Understanding the causes of pediatric stroke is crucial for effective management and prevention.

Purpose of the Study:

  • To review and classify the etiologies of cerebral infarcts in children aged 0-15 years.
  • To identify common causes and risk factors for stroke in pediatric populations.

Main Methods:

  • Retrospective review of 39 children (2 months to 15 years) diagnosed with cerebral infarcts.
  • Classification of infarct etiologies using modified Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria.
  • Analysis of etiological categories: atherosclerosis, cardioembolic, small vessel occlusion, other, and undetermined.

Main Results:

  • The largest etiological group was 'other' (56.4%), with dehydration and septic shock causing brain hypoperfusion and watershed infarcts being most common.
  • Nine children (23%) had undetermined causes, and 7 (17.9%) had cardioembolic strokes.
  • No cases of atherosclerosis in large arteries were identified.

Conclusions:

  • A significant proportion of pediatric cerebral infarcts remain without a defined cause, necessitating improved laboratory diagnostics.
  • Dehydration is a prominent identified cause, underscoring the importance of preventive health actions for infants and children.
  • Further research is needed to elucidate the causes of pediatric stroke and develop targeted interventions.

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