Related Experiment Video
Updated: Aug 6, 2026

Basics of Multivariate Analysis in Neuroimaging Data
Published on: July 25, 2010
Presentation of multivariate data for clinical use: The Framingham Study risk score functions
Lisa M Sullivan1, Joseph M Massaro, Ralph B D'Agostino
1Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, MA 02115, USA. lsull@bu.edu
Abstract:
The Framingham Heart Study has been a leader in the development and dissemination of multivariable statistical models to estimate the risk of coronary heart disease. These models quantify the impact of measurable and modifiable risk factors on the development of coronary heart disease and can be used to generate estimates of risk of coronary heart disease over a predetermined period, for example the next 10 years. We developed a system, which we call a points system, for making these complex statistical models useful to practitioners. The system is easy to use, it does not require a calculator or computer and it simplifies the estimation of risk based on complex statistical models. This system represents an effort to make available a tool for clinicians to aid in their decision-making process regarding treatment and to assist them in motivating patients toward healthy behaviours. The system is also readily available to patients who can easily estimate their own coronary heart disease risk and monitor this risk over time.
Related Concept Videos
Study Design in Statistics
Does aspirin reduce the risk of heart attacks? Is one brand of fertilizer more effective at growing roses than another? Is fatigue as dangerous to a driver as the influence of alcohol? Questions like these are answered using randomized experiments with proper...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Relative Risk
Statistical Methods for Analyzing Epidemiological Data
Statistical Software for Data Analysis and Clinical Trials
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

