[Endometrial carcinoma: which radiotherapy for which patient?]

The endometrial carcinoma is the third most common cancer in women. The endometrioid adenocarcinomas represent 75% to 80% of the pathologic sub-types, and 90% of the lesions are stages I or II at diagnosis. The treatment strategies are based upon surgery and radiotherapy, but the respective place of external irradiation and vaginal cuff brachytherapy is not strictly established. The role of the pelvic lymphadenectomy and the role of chemotherapy for aggressive histologies or locally advanced diseases remain also controversial issues. The question "which radiotherapy for which patient?" is still a current question, however, the answers we will bring do not permit yet to remove all uncertainties.