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Updated: Aug 24, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
High-frequency ultrasound of anterior segment retinoblastoma
Paul T Finger1, Seth W Meskin, H Jay Wisnicki
1New York Eye Cancer Center, The New York Eye and Ear Infirmary, 115 East 61st Street, New York, NY 10021, USA. pfinger@eyecancer.com
Purpose:
To evaluate anterior segment retinoblastoma with high-frequency ultrasound.
Design:
Interventional case report.
Methods:
An 11-year-old boy with a total retinal detachment and multiple white anterior chamber nodules was examined with high-frequency ultrasound before enucleation of the globe.
Results:
Multiple solid and cystic nodular tumors were found in the anterior chamber angle. With high-frequency ultrasound, tumor was discovered posterior to the iris, over the ciliary processes, and on the lens capsule. No calcifications were noted. Other findings included angle closure related to iris neovascularization and uveal thickening.
Conclusion:
High-frequency ultrasound can be used to evaluate retinoblastoma extension into the anterior segment. These images may be used for comparison in future cases of retinoblastoma with anterior chamber invasion.