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Updated: Aug 24, 2026
Transmitochondrial Cybrid Generation Using Cancer Cell Lines
Published on: March 17, 2023
Investigation of common mitochondrial point mutations in Korea
Seon-Joo Kwon1, Sung-Sup Park, Jong-Min Kim
1Department of Neurology, Seoul National University Medical Research Center, Clinical Research Institute, Seoul, Korea.
Abstract:
Between 1997 and 2002, 65 patients with suspected mitochondrial diseases were screened for the mitochondrial point mutations A3243G, T3271C, A8344G, and T8356C. Among these patients, 15 were found to have one of these mutations: 12 with A3243G and 3 with A8344G. The phenotypes of A3243G and A8344G mutations were MELAS and MERRF, respectively. Many asymptomatic family members had the same mutations. In this report, detailed clinical and laboratory findings are presented.
