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Obesity exacerbates oxidative stress levels after acute exercise
Heather K Vincent1, Jason W Morgan, Kevin R Vincent
1Center for the Study of Complementary and Alternative Therapies (CSCAT), University of Virginia Health System, Charlottesville, VA 22908, USA. hkv5d@virginia.edu
Medicine and Science in Sports and Exercise
|May 6, 2004
Summary
Obesity exacerbates exercise-induced oxidative stress, with higher lipid peroxidation observed in obese individuals after both resistance and aerobic exercise. Antioxidant intake and oxygen consumption may influence these responses.
Area of Science:
- Exercise Physiology
- Biochemistry
- Nutritional Science
Background:
- Obesity is associated with increased oxidative stress.
- The impact of different exercise types on oxidative stress in obese versus nonobese individuals requires further investigation.
Purpose of the Study:
- To compare oxidative stress markers and antioxidant capacity between nonobese and obese participants following acute resistance exercise (RX) and aerobic exercise (AX).
Main Methods:
- Blood samples were analyzed for lipid hydroperoxides (PEROX) and malondialdehyde (TBARS) pre- and post-exercise in 28 nonobese and obese participants.
- Total antioxidant status (TAS), oxygen consumption (VO2), and minute ventilation (VE) were also measured during RX and AX sessions.
Main Results:
- Both RX and AX elevated PEROX and TBARS in all participants, with significantly greater increases in the obese group.
- Obese participants showed higher TBARS and PEROX elevations post-exercise compared to nonobese individuals.
- Correlations were found between exercise-induced PEROX changes and factors like body fat, vitamin intake, VO2, and plasma triglycerides.
Conclusions:
- Acute resistance and aerobic exercise increase lipid peroxidation, an effect that is more pronounced in obese individuals.
- Potential mechanisms contributing to these findings include plasma triglycerides, oxygen consumption, and antioxidant intake.
- The specific pathways may differ between resistance and aerobic exercise modalities.