Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

How to avoid false-negative dynamic sentinel node procedures in penile carcinoma.

B K Kroon1, S Horenblas, S H Estourgie

  • 1Department of Urology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

The Journal of Urology
|May 6, 2004
PubMed
Summary

This study evaluated false-negative dynamic sentinel node biopsies in penile cancer patients. Adaptations to the procedure were made to improve accuracy and reduce recurrence rates.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Five-year analysis of neoadjuvant dabrafenib and trametinib for stage III melanoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2024
Same author

Hypofractionated or Conventionally Fractionated Adjuvant Radiotherapy After Regional Lymph Node Dissection for High-Risk Stage III Melanoma.

Clinical oncology (Royal College of Radiologists (Great Britain))·2022
Same author

Psoas hitch procedure in 166 adult patients: The largest cohort study before the laparoscopic era.

BJUI compass·2022
Same author

[Large-Vessel Vasculitis and Giant-Cell Arteritis accompanied by concomitant abnormalities on <sup>18</sup>F-FDG PET/CT imaging].

Revista espanola de medicina nuclear e imagen molecular·2022
Same author

Does <sup>99m</sup>Tc-tilmanocept, as next generation radiotracer, meet with the requirements for improved sentinel node imaging?

Revista espanola de medicina nuclear e imagen molecular·2021
Same author

Predicting recurrence in patients with sentinel node-negative melanoma: validation of the EORTC nomogram using population-based data.

The British journal of surgery·2021

Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Penile carcinoma management requires accurate nodal staging.
  • Sentinel lymph node biopsy (SLNB) is a minimally invasive staging technique.

Purpose of the Study:

  • To evaluate the false-negative rate of dynamic sentinel node biopsy (DSNB) in penile squamous cell carcinoma.
  • To identify causes of false-negative DSNB results.
  • To implement procedural improvements for DSNB in penile cancer.

Main Methods:

  • A retrospective analysis of 123 penile squamous cell carcinoma patients undergoing DSNB between 1994 and 2003.
  • Analysis of regional recurrence rates and causes of false-negative DSNB.

Main Results:

  • Metastasis was detected in the sentinel node of 28 (23%) patients.

Related Experiment Videos

  • A false-negative rate of 18% (6 of 34) was observed.
  • Causes included tumor blockage, rerouting, sampling error, and low radioactivity.

    • Conclusions:

    • False-negative DSNB results in penile cancer necessitate procedural modifications.
    • Enhanced pathological analysis (serial sectioning, immunohistochemistry) and preoperative imaging (ultrasound with FNA) were implemented.
    • Groin exploration without visualized nodes and intraoperative palpation were introduced to improve detection.