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Stuttering priapism associated with withdrawal from sustained-release methylphenidate
Richard H Schwartz1, H Gil Rushton
1Department of Pediatrics, Inova Fairfax Hospital for Children, Falls Church, Virginia, USA. RHW738@aol.com
The Journal of Pediatrics
|May 6, 2004
Summary
Stuttering priapism, a painful condition, was observed in an adolescent after discontinuing methylphenidate. This is the first reported case linking stimulant medication withdrawal to stuttering priapism in attention deficit hyperactivity disorder treatment.
Area of Science:
- Urology
- Pediatrics
- Pharmacology
Background:
- Stuttering priapism is characterized by recurrent, prolonged, and painful erections.
- Attention deficit hyperactivity disorder (ADHD) is commonly treated with stimulant medications.
- Methylphenidate is a widely prescribed stimulant for ADHD.
Observation:
- An adolescent patient experienced stuttering priapism.
- The onset of priapism coincided with the withdrawal from sustained-release methylphenidate.
- This represents a novel clinical observation linking stimulant withdrawal to priapism.
Findings:
- The case report details a unique instance of stuttering priapism in an adolescent.
- The patient's priapism was associated with the cessation of methylphenidate therapy.
- This is the first documented case of stuttering priapism linked to stimulant drug withdrawal for ADHD.
Implications:
- This finding suggests a potential adverse effect of methylphenidate withdrawal.
- Clinicians should consider priapism in the differential diagnosis of painful erections in adolescents on stimulants.
- Further research is warranted to explore the relationship between stimulant medications and priapism.