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Updated: Aug 24, 2026

A Micropatterning Assay for Measuring Cell Chirality
Published on: March 11, 2022
A new simple procedure for discriminating between deracemization and an induced CD Effect in chiral recognition
Francesca Ceccacci1, Marco Diociaiuti, Luciano Galantini
1CNR Istituto di Metodologie Chimiche-Sezione Meccanismi di Reazione, and Università di Roma "La Sapienza", P.le A. Moro 5, 00185 Roma, Italy.
Abstract:
A CD band in chiral recognition experiments on racemic stereolabile compounds can be ascribed either to deracemization or to a solely induced CD effect. A procedure is presented that allows one to discriminate positively between the two phenomena. The procedure, based on CD spectroscopy, was used in experiments on racemic biphenylic derivatives in aggregates formed by enantiopure surfactants. In addition to demonstrating a deracemization event, the procedure allowed us to measure the enantiomeric excess.
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