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Multimodal treatment for resectable epithelial type malignant pleural mesothelioma
Ichiro Yoshino1, Masafumi Yamaguchi, Tatsuro Okamoto
1Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan. iyoshino@surg2.med.kyushu-u.ac.jp
Background:
Malignant pleural mesothelioma is a rare malignancy. The outcome remains poor despite complete surgical resection.
Patients And Methods:
Eleven patients with histologicaly proven epithelial type malignant pleural mesothelioma undergoing extrapleural pneumonectomy with systemic chemotherapy and/or radiotherapy before and after surgical resection were retrospectively reviewed.
Results:
Ten out of 11 patients underwent complete surgical resection, of these 7 patients had stage I disease. Of these 7 patients, 5 are alive without any recurrence, a 2-year survival rate of 80% was observed in this group. There was no operative mortality or morbidity.
Conclusion:
Extrapleural pneumonectomy with perioperative adjuvant treatment is safe and effective procedure for epithelial type malignant pleural mesothelioma.