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Updated: Aug 15, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
[Coagulation factors and hemostatic agents]
1Laboratoire d'Hémostase, Cliniques Universitaires Saint-Luc. deneys@sang.ucl.ac.be
Insights
Clinicians can choose from many drugs to prevent or treat bleeding. A rational approach requires identifying the cause of bleeding and considering medication costs for effective treatment.
Area of Science:
- Pharmacology
- Hematology
- Clinical Therapeutics
Context:
- Numerous therapeutic agents exist for preventing or treating hemorrhagic events.
- Effective management necessitates an etiological approach to guide drug selection.
Purpose:
- To emphasize the importance of etiological diagnosis in the rational use of antithrombotic and hemostatic agents.
- To highlight the need for cost-effectiveness analysis in prescribing medications for hemorrhagic conditions.
Summary:
- A wide array of drugs are available for managing bleeding disorders.
- Identifying the specific cause of a hemorrhagic event is paramount for selecting appropriate therapy.
- Clinicians must consider the financial implications and cost-effectiveness of different treatment options.
Impact:
- Facilitates rational prescribing of medications for hemorrhagic conditions.
- Promotes evidence-based decision-making by integrating clinical efficacy with economic considerations.
- Aims to optimize patient outcomes while managing healthcare resource utilization.
Abstract:
A large variety of therapeutic agents are available to prevent or treat hemorrhagic events. An etiologic focusing is essential to permit a rational use of these drugs. Some medications are cheap, others are very expensive, and the clinician has to evaluate the cost-effectiveness of his prescription in each situation.
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