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[Studies on the efficient application by STKS and 8200].

S Mishima1, T Unshima, Y Yoshida

  • 1Department of Laboratory Medicine, Shimane Medical College, Izumo.

Rinsho Byori. the Japanese Journal of Clinical Pathology
|June 1, 1992
PubMed
Summary

Automated systems like STKS and Cell Analyzer 8200 offer rapid differential leukocyte counts, aiding in identifying abnormalities. Combining these with manual methods improves lab efficiency and reduces unnecessary manual differentials.

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Area of Science:

  • Hematology
  • Clinical Pathology
  • Laboratory Medicine

Context:

  • Evaluating automated differential leukocyte counting systems is crucial for efficient clinical diagnostics.
  • Traditional manual methods serve as a benchmark for automated cell analysis.
  • The STKS and Cell Analyzer 8200 represent advanced automated hematology platforms.

Purpose:

  • To assess the utility of the STKS (Coulter) and Cell Analyzer 8200 (Hitachi) for differential leukocyte counts.
  • To compare the performance of these automated systems against the traditional manual method.
  • To determine the potential of automated systems in improving laboratory turnaround times.

Summary:

  • The STKS system provides rapid 5-part differential leukocyte counts, effectively identifying significant abnormalities but potentially missing atypical lymphocytes (ATL cells) and low erythroblasts.

Related Experiment Videos

  • The Cell Analyzer 8200, using automated slide preparation and image analysis, shows good correlation with manual counts but also misses low erythroblasts and ATL cells, with a lower cell count per minute.
  • Implementing automated systems, including STKS and Cell Analyzer 8200, with carefully selected cut-off limits, enhances laboratory efficiency and reduces the need for manual differentials.

    • Impact:

    • Automated differential leukocyte counts significantly improve laboratory turnaround time for blood assessments.
    • These systems can help reduce the frequency of unnecessary manual differential leukocyte counts.
    • Integration of automated and manual methods optimizes diagnostic workflows in hematology laboratories.