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A collaborative database of inbred mouse strain characteristics.

Stephen C Grubb1, Gary A Churchill, Molly A Bogue

  • 1The Jackson Laboratory, Bar Harbor, ME 04609, USA. phenome@jax.org

Bioinformatics (Oxford, England)
|May 8, 2004
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Summary

The Mouse Phenome Database (MPD) consolidates physiological, anatomical, and behavioral data from mouse strains. This resource aids research into human health by providing standardized characterization data.

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Area of Science:

  • Genomics and Bioinformatics
  • Comparative Medicine
  • Translational Research

Background:

  • The Mouse Phenome Database (MPD) was developed to centralize mouse strain characterization data.
  • It integrates physiological, anatomical, behavioral, and genotypic data.

Purpose of the Study:

  • To create a unified, accessible resource for mouse phenome data.
  • To facilitate research by providing standardized data for 40 inbred mouse strains.

Main Methods:

  • Data collection from the scientific community.
  • Integration of phenotypic and genotypic data into a common framework.
  • Tabulation of data by mouse strain and sex.

Main Results:

  • The MPD consolidates approximately 500 phenotypic parameters relevant to human health.
  • Data is contributed voluntarily by numerous investigators and laboratories.
  • The database focuses on 40 inbred mouse strains.

Conclusions:

  • The MPD serves as a valuable resource for comparative genomics and phenomics research.
  • Standardized data facilitates the study of genotype-phenotype relationships.
  • This database supports research endeavors in human health and disease.