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[Collagen changes of allografting an acellular dermal matrix]
Meng-hua Huo1, Ke-ming Qi, Jin-jing Huang
1Plastic Surgery Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100041, China.
Abstract
Objective:
To evaluate the collagen changes of allografting an acellular dermal matrix (allo-ADM).
Methods:
The allo-ADM was grafted underneath the skin of SD rats. The content of collagen and the proportion of type I to III collagen was examined with a biochemical assay.
Result:
The content of collagen and the proportion of type I to III collagen in the allo-ADM group showed no significant changes.
Conclusion:
The allo-ADM could keep long time in the body and it may be an ideal material for soft tissue filling.