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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
Paediatric open globe injuries. Visual outcome and risk factors for endophthalmitis
Subina Narang1, Vishali Gupta, Prabhat Simalandhi
1Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Insights
Delayed repair of pediatric open globe injuries increases endophthalmitis risk. Early intervention and parental supervision are crucial for preventing this severe complication in children with eye trauma.
Area of Science:
- Ophthalmology
- Pediatric Trauma
- Infectious Disease
Background:
- Open globe injuries represent a significant cause of vision loss in children.
- Post-traumatic endophthalmitis is a severe complication that can lead to poor visual outcomes.
Purpose of the Study:
- To determine the incidence and outcomes of pediatric open globe injuries.
- To identify risk factors associated with post-traumatic endophthalmitis in children.
Main Methods:
- Retrospective analysis of 72 pediatric cases of open globe injury.
- Data collected over a 3-year period (January 1998 - December 2000).
- Analysis included injury causes, visual acuity outcomes, and endophthalmitis development.
Main Results:
- Common causes included sports, bow and arrow, and household injuries.
- 52.86% of patients achieved visual acuity of >= 3/60.
- Delayed primary repair (>24 hours) was linked to poorer visual acuity and increased endophthalmitis risk.
Conclusions:
- Delayed surgical repair, bow and arrow, and household injuries are significant risk factors for endophthalmitis.
- Early referral and enhanced parental supervision can potentially reduce endophthalmitis incidence.
Purpose:
To study the incidence of open globe injuries and the outcome in children, and to study the risk factors for post-traumatic endophthalmitis.
Methods:
Paediatric patient population. Retrospective analysis of 72 consecutive cases of open globe injury over 3 years (January 1998 to December 2000).
Results:
The cause of trauma was sports related (n = 18), home-made bow and arrow (n = 16), household kitchen injuries (n = 10), cracker injuries (n = 7) and other miscellaneous outdoor activities (n = 16). In 5 children the cause could not be ascertained. Visual acuity of > or = 3/60 in the injured eye at the last follow-up examination was recorded in 37 of 70 patients (52.86%) whose visual acuity could be tested. The final visual acuity was significantly poorer in eyes where primary repair was delayed beyond 24 hours of injury (P < 0.05). Post- traumatic endophthalmitis developed in 39 of 72 (54.16%) eyes. Bow and arrow and household injuries (P < 0.5) and eyes in which primary repair was delayed beyond 24 hours of injury (P < 0.01) had a higher risk of endophthalmitis in univariate analysis. In multivariate analysis delayed repair was the only significant risk factor for the occurrence of endophthalmitis (P = 0.014).
Conclusion:
Delayed repair, bow and arrow injuries and household injuries were associated with significantly higher risk of endophthalmitis. The incidence of endophthalmitis can be reduced by early referral of trauma cases and parental supervision.
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