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Related Experiment Videos

Partial RF echo-planar imaging with the FAISE method. II. Contrast equivalence with spin-echo sequences.

P S Melki1, F A Jolesz, R V Mulkern

  • 1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Magnetic Resonance in Medicine
|August 1, 1992
PubMed
Summary

Fast acquisition interleaved spin-echo (FAISE) MRI sequences closely mimic spin-echo contrast for T1 and T2 weighting. Minor differences arise from echo spacing and magnetization transfer effects in FAISE.

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Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Biomedical Engineering
  • Radiology

Background:

  • Fast acquisition interleaved spin-echo (FAISE) and dual-echo FAISE (DEFAISE) are advanced MRI techniques.
  • These methods use phase-encode reordering to control T2 contrast via pseudo-echo time (pTE).
  • T1 weighting can be introduced by adjusting the repetition time (TR) in FAISE sequences.

Purpose of the Study:

  • To quantitatively assess the agreement between FAISE/DEFAISE and conventional spin-echo (SE) methods.
  • To determine how well FAISE T1 and T2 contrast characteristics correlate with established SE techniques.
  • To identify potential discrepancies and their underlying mechanisms.

Main Methods:

  • Signal intensities from FAISE acquisitions were compared with those from equivalent Carr-Purcell-Meiboom-Gill (CPMG) acquisitions.

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  • Acquisitions were performed on both phantoms and human subjects.
  • Analysis focused on correlating contrast characteristics between the two sequence types.

    • Main Results:

    • FAISE demonstrated a high correlation with CPMG sequences for contrast characteristics in both phantoms and human brains.
    • Differences were observed, primarily attributed to echo spacing-dependent mechanisms (spin-spin coupling, magnetic susceptibility) in conventional SE.
    • FAISE showed increased sensitivity to magnetization transfer effects compared to conventional SE.

    Conclusions:

    • FAISE and DEFAISE offer comparable T1 and T2 contrast to conventional spin-echo sequences.
    • The choice of echo spacing significantly influences contrast, leading to variations between FAISE/CPMG and conventional SE.
    • FAISE's enhanced sensitivity to magnetization transfer warrants consideration in specific imaging applications.