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Androgen receptor abnormality in X-linked spinal and bulbar muscular atrophy
T Matsuura1, T Demura, Y Aimoto
1Department of Neurology, Hokkaido University School of Medicine, Sapporo, Japan.
Neurology
|September 1, 1992
Abstract:
X-linked spinal and bulbar muscular atrophy (SBMA) is usually associated with feminization and hypogonadism. We were unable to find androgen receptor (AR) in the scrotal skin of three patients with SBMA, and propose that AR abnormality is the cause of the disease.