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Rheumatoid necroses in the forefoot
Irina Berger1, Klaus-Dieter Martens, Carola Meyer-Scholten
1Institute of Pathology, Heidelberg University, Germany. Irina_Berger@med.uni-heidelberg.de
Foot & Ankle International
|May 12, 2004
Summary
Rheumatoid necrosis (RN) is common in the forefoot of rheumatoid arthritis (RA) patients, often causing pain and foot deformities. This condition frequently goes undetected clinically, impacting patient well-being.
Area of Science:
- Rheumatology
- Pathology
- Orthopedics
Background:
- Rheumatoid necrosis (RN) in the forefoot is poorly understood.
- Its incidence and specific morphological characteristics remain largely unknown in clinical settings.
Purpose of the Study:
- To investigate the incidence and morphological features of rheumatoid necroses in the forefoot.
- To assess the clinical relevance of RN in patients with seropositive rheumatoid arthritis.
Main Methods:
- Morphological examination of biopsy material from 223 patients.
- Evaluation of RN incidence and features in the forefoot.
Main Results:
- Rheumatoid necrosis was identified in 65% of patients, often without prior clinical suspicion.
- RN was clinically correlated with pain in 69% of affected cases.
Conclusions:
- Rheumatoid necrosis is a significant contributor to forefoot pain and deformation in seropositive RA.
- Recognizing RN is crucial for managing clinical outcomes in rheumatoid arthritis patients.