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Updated: Aug 24, 2026

Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
Rheumatoid necroses in the forefoot
Irina Berger1, Klaus-Dieter Martens, Carola Meyer-Scholten
1Institute of Pathology, Heidelberg University, Germany. Irina_Berger@med.uni-heidelberg.de
Background:
The incidence and morphological features of rheumatoid necroses (RN) in the forefoot are unknown.
Methods:
Biopsy material from 223 patients with seropositive rheumatoid arthritis (RA) was examined morphologically. The incidence and morphological features of RN in the forefoot were evaluated.
Results:
RN was found in 65% of cases, which had not been suspected clinically. It was correlated with pain in 69% of cases.
Conclusions:
Rheumatoid necrosis contributes to the development of pain and foot deformation. It can be a significant factor worsening the clinical behavior in seropositive RA patients.
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