Related Experiment Videos
P3 recordings in patients with bilateral temporal lobe lesions
M Onofrj1, T Fulgente, D Nobilio
1Department of Neurology and Behavioral Sciences, State University of Chieti, Italy.
Neurology
|September 1, 1992
Abstract:
We recorded event-related potentials to an acoustic "oddball" paradigm from 19 scalp derivations in five patients (three women and two men; age range, 44 to 56) who had global amnesia following encephalitis. CT and MRI showed severe bilateral lesions of anterior and midtemporal lobes. A P3 component, with a peak latency within the normal limits for age-matched controls, was recorded to "target" stimuli in four patients from all leads except Fp1, Fp2, F7, F8, T3, and T4. In the fifth patient, the P3 peak was delayed.