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Updated: Aug 24, 2026

Intermittent Binge-Intake Model in Mice
Published on: January 10, 2025
Energy and macronutrient intake in bulimia nervosa
Georg W Alpers1, Brunna Tuschen-Caffier
1Department of Biological Psychology, Clinical Psychology, and Psychotherapy, Julius-Maximilians Universität Würzburg, Marcusstrasse 9-11, Wuerzburg D-97070, Germany. alpers@psychologie.uni-wuerzburg.de
Abstract:
Energy deprivation and malnutrition are often thought to be key factors in the maintenance of bulimia nervosa (BN). Our review shows that it is unclear how much energy is actually available to BN patients' metabolism because the contribution of food consumed during binge eating is generally neglected. Also, there is little evidence for another key hypothesis that binge-eating episodes are triggered by carbohydrate craving. This study examined energy consumption and macronutrient composition of meals and binge-eating episodes in food diaries. Forty female BN patients, 40 female panic disorder (PD) patients, and 40 healthy women recorded their food intake while in their natural environment during two consecutive days. We did not find the expected evidence for chronic energy deprivation and malnutrition in BN patients. Also, there was no evidence that carbohydrate craving drives binge eating. The implications for models of BN and for treatments targeting eating behavior are discussed.
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