Fast relaxation processes and structural changes in immunoactive biomolecules
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Updated: Aug 24, 2026

NMR 15N Relaxation Experiments for the Investigation of Picosecond to Nanoseconds Structural Dynamics of Proteins
Published on: November 1, 2024
N A Borisevich1, V L Dubovsky, A L Mikhalchuk
1Institute of Molecular & Atomic Physics, National Academy of Sciences of Belarus, 70 F. Skaryna Avenue, 220072 Minsk, Belarus.
Abstract:
Based upon an analysis of the absorption spectra, the fluorescence and fluorescence excitation spectra, and the lifetime of the excited states of aqueous solutions (pH 7.4) of 2,3-dimethoxy-8-azagona-1,3,5(10),13-tetraene-12,17-dione, it is established that two centers of different type exist: one emits long-wave (L-centers) and the other short-wave (S-centers) fluorescence. Irradiation of solutions increases the number of L-centers and greatly decreases that of S-centers. Examination of the picosecond transient absorption spectra and their kinetics revealed that the initial photochemical stage is defined as the ionization of a considered molecule and the subsequent one, as the formation, most probably, of the dehydroderivative of a parent molecule.
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