Related Experiment Video
Updated: Aug 24, 2026

A Microfluidic System for Modeling Endothelial Dysfunction under Combined Physiological Pulsatile Shear Stress and Oscillatory Hyperglycemia
Published on: May 12, 2026
Computer simulation and mathematical model of blood glucose behaviour
Mujo Hebibovic1, Bakir Lacevic, Jasmin Velagic
1Faculty of Electrical Engineering, University of Sarajevo, B&H.
Abstract:
This work is considering three significant factors that affect blood glucose level: food intake, hereditary predisposition and stress. Goal of this paper is to observe blood sugar level in human organism as a dynamic MISO (Multi Input, Single Output) system, and to describe it with differential equations and control system blocks. The system has three inputs; food (carbohydrates), hereditary factor and stress, and a single output--blood glucose level. Basically, several logical assumptions have been made, as the result of few medical researches. A model that gives outputs, very similar to real ones (measurements of glucose level in human body) is used for more detailed analysis. This model is very suitable for computer simulations and it can easily be tested for different input arrangements. Using this property of the system, several modes of food consumption have been proposed, in order to retain blood sugar level inside recommended limits.
More Related Videos
Related Concept Videos
Pharmacokinetic Models: Comparison and Selection Criterion
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.
Glucose Homeostasis: Regulation of Blood Glucose
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are co-secreted in...
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...
Pharmacokinetic Models: Overview
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal assumptions,...
Fundamental Mathematical Principles in Pharmacokinetics: Calculus and Graphs
On the other hand, integral calculus focuses on...

