Jove
Visualize
Contact Us

Related Experiment Videos

[Suicidal buflomedil intoxication].

Bernward Babel1, Thomas Tatschner, Dieter Patzelt

  • 1Institut für Rechtsmedizin der Universität Würzburg.

Archiv Fur Kriminologie
|May 13, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fatal visit to the general practitioner.

Archiv fur Kriminologie·2018
Same author

Suicidal carbon monoxide poisoning using a gas-powered generator.

Forensic science international·2014
Same author

[Vehicle-assisted suicide with a nylon rope causing complete decapitation].

Archiv fur Kriminologie·2013
Same author

Neuron-specific alterations in signal transduction pathways associated with Alzheimer's disease.

Journal of Alzheimer's disease : JAD·2013
Same author

Fatal visit to the dentist.

International journal of legal medicine·2013
Same author

Neuron-specific mitochondrial DNA deletion levels in sporadic Alzheimer's disease.

Current Alzheimer research·2013
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

A young woman died after a buflomedil overdose. High buflomedil concentrations were found in body fluids, and autopsy revealed anemia linked to its vasodilating effects.

Area of Science:

  • Toxicology
  • Pharmacology
  • Forensic Medicine

Background:

  • Buflomedil is a medication with known vasodilating properties.
  • Overdose cases require thorough toxicological and pathological investigation.

Observation:

  • A fatal suicidal intoxication case involving buflomedil overdose in a young woman is presented.
  • The patient died 17 hours post-ingestion.
  • Autopsy and histological examination were performed.

Findings:

  • High concentrations of buflomedil were detected in various biological samples, including heart blood (24.5 µg/ml), cerebrospinal fluid (21.3 µg/ml), bile (39.1 mg/ml), and urine (138.6 mg/ml).
  • Significant anemia of internal organs was observed during autopsy.
  • This anemia is hypothesized to be a consequence of buflomedil's peripheral vasodilatory action.

Related Experiment Videos

Implications:

  • This case highlights the potential toxicity and lethal effects of buflomedil overdose.
  • Understanding the pharmacokinetic profile and pathological consequences is crucial for clinical management and forensic analysis.
  • The vasodilating effect of buflomedil may contribute to severe systemic complications in overdose scenarios.