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Updated: Aug 24, 2026

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
Published on: September 6, 2017
Antierythropoietin antibody-induced pure red cell aplasia: posttransplant evolution
Angel Alonso Melgar1, Marta Melgosa Hijosa, Rafael Pardo de la Vega
1Pediatric Nephrology Unit, Hospital "La Paz", Madrid, Spain.
Abstract:
Pure red cell aplasia is a rare complication of recombinant human erythropoietin (rHuEPO) treatment, which physicians should consider once the more frequent causes of hyporegenerative anemia have been excluded. To our knowledge, no pediatric cases have been described. In our patient, cyclosporin A treatment enabled a reduction in the number of transfusions and the risk of hyperimmunization. After transplantation, our patient's hemoglobin level has remained normal and stable.
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