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[Adjustive effect of yi qi tong lin chongji on the three growth factors in rats prostatic tissues]
Zheng-guo Mi1, Su-xiang Liu, Yong-qing Cao
1First Hospital, Shanxi Medical University, Taiyuan 030001, Shanxi, China.
Objective:
To study the mechanisim of Yi Qi Tong Lin Chingji in treating benign prostatic hyperplasia.
Method:
The expressions of VEGF, bFGF and TGF beta 1 in prostatic hyperplasia model rats were examined by immunohistochemistry. 8 rats were in contrastive group, 24 influenced by Yi Qi Tong Ling Chingji and Prostacar.
Result:
The expressions of VEGF and bFGF were significantly difference, but the expression of TGF beta 1 was not significant. (P < 0.01). The expression of VEGF and bFGF were significant in contrastive group to the high-dose of Yi Qi Tong Ling Chingji and Prostacar group (P < 0.05) but were not significant to the low-dose of Yi Qi Tong Ling Chingji group. There was no significant difference between high-dose of Yi Qi Tong Ling Chingji and Prostacar group and three growth factors.
Conclusion:
Yi Qi Tong Ling Chingji inhibit the expression of VEGF and bFGF in BPH so as to decrease the volume of prostate.
