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Serum interleukin (IL-1 beta) in patients with diffuse scleritis
G N Palexas1, A Puren, N Savage
1Department of Ophthalmology, University of the Witwatersrand, Johannesburg, South Africa.
Scandinavian Journal of Immunology. Supplement
|January 1, 1992
Abstract:
Scleritis is a painful, destructive inflammatory eye disease. We measured serum IL-1 beta in ten patients with diffuse scleritis and in control subjects matched for age and sex. Patients with diffuse scleritis were found to have significantly elevated serum concentrations of IL-1 beta in comparison to normal subjects (P less than 0.02). The results suggest that IL-1 beta is associated with diffuse scleritis and may influence scleral breakdown in diffuse scleritis.