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Updated: Jul 11, 2026
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Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Primitive vertebrobasilar system associated with a ruptured aneurysm
Kenji Yagi1, Koichi Satoh, Junichiro Satomi
1Department of Neurosurgery, School of Medicine, University of Tokushima, Tokushima, Japan.
AJNR. American Journal of Neuroradiology
|May 14, 2004
Summary
Persistent primitive lateral vertebrobasilar (PPLVB) anastomosis is a rare fetal remnant. This case presents a unique variant where PPLVB primarily supplied the basilar artery due to underdeveloped vertebrobasilar junctions, potentially leading to aneurysmal rupture.
Area of Science:
- Neurology
- Vascular Anatomy
- Embryology
Background:
- Persistent primitive lateral vertebrobasilar (PPLVB) anastomosis is an exceedingly rare remnant of early human embryonic development.
- Previous reports of PPLVB occurrence are exceptionally scarce, with only one documented instance.
Observation:
- This study details a novel variant of PPLVB.
- In this variant, the basilar artery received its primary blood supply from the PPLVB anastomosis.
- This occurred due to contralateral incomplete development and ipsilateral aplasia of the vertebrobasilar junction.
Findings:
- The vertebrobasilar junction exhibited asymmetrical development, with one side being hypoplastic and the other aplastic.
- The PPLVB served as the dominant feeder vessel for the basilar artery in this unique anatomical configuration.
Implications:
- The abnormal hemodynamic stress within this variant PPLVB may predispose individuals to aneurysmal formation and rupture.
- Understanding such rare vascular anomalies is crucial for accurate diagnosis and management of cerebrovascular diseases.
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