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MR findings in Hashimoto encephalopathy
Yonung Min Song1, Dae Won Seo, Gregory Youngnam Chang
1Department of Neurology, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.
AJNR. American Journal of Neuroradiology
|May 14, 2004
Summary
Hashimoto encephalopathy presents with diverse MR imaging findings, mimicking conditions like stroke or tumors. This variability highlights the need for careful diagnosis in patients with this neurological disorder.
Area of Science:
- Neurology
- Radiology
- Immunology
Background:
- Hashimoto encephalopathy is an autoimmune disorder associated with Hashimoto thyroiditis.
- Its clinical presentation can be variable, posing diagnostic challenges.
Observation:
- A 35-year-old Korean woman exhibited Hashimoto encephalopathy over five years.
- Her MR imaging revealed transient subcortical ischemia and evolving multifocal signal changes.
- Unilateral cerebellar atrophy was also noted.
Findings:
- The MR imaging appearance of Hashimoto encephalopathy demonstrated significant variability.
- Findings simulated ischemic stroke, multiple tumors or granulomas, and degenerative processes.
Implications:
- The diverse MR imaging manifestations of Hashimoto encephalopathy can mimic other neurological conditions.
- Radiologists and clinicians should consider Hashimoto encephalopathy in the differential diagnosis of unexplained neurological symptoms with varied imaging findings.
- This case underscores the importance of integrating clinical and imaging data for accurate diagnosis.