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Topical anaesthetic use for treating premature ejaculation: a double-blind, randomized, placebo-controlled study
1Urology Surgery Service, Marieta Konder Bornhausen Hospital, Itajaí, Brazil. wbusato@melim.com.br
BJU International
|May 15, 2004
Summary
Topical anesthetic cream, specifically a lidocaine-prilocaine mixture, significantly increased the intravaginal ejaculatory latency time (IELT) in men experiencing premature ejaculation (PE). This topical anesthetic may be an effective treatment for PE.
Area of Science:
- Urology
- Dermatology
- Sexual Health
Background:
- Premature ejaculation (PE) is a common sexual dysfunction.
- Penile hypersensitivity is a potential contributing factor to PE.
Purpose of the Study:
- To evaluate the efficacy of a topical anesthetic cream in managing premature ejaculation (PE).
- To determine if a lidocaine-prilocaine mixture can improve ejaculatory control.
Main Methods:
- A randomized controlled trial involving 42 men with PE.
- Group A received a lidocaine-prilocaine anesthetic cream; Group B received an inert cream.
- Intravaginal ejaculatory latency time (IELT) was the primary outcome measure.
Main Results:
- Group A demonstrated a statistically significant increase in mean IELT (from 1.49 to 8.45 minutes, P < 0.001).
- Group B showed no significant change in mean IELT (from 1.67 to 1.95 minutes, P > 0.05).
Conclusions:
- Topical anesthetic cream, particularly the lidocaine-prilocaine mixture, shows promise as an effective treatment for premature ejaculation.
- Further research is warranted to confirm these findings and explore optimal application protocols.