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Conservative treatment in noninvasive breast cancer
Nuria Rodríguez1, Xavier Sanz, Manuel Algara
1Institut d'Oncologia Radioterápica, Hospital de l'Esperança, IMAS, Barcelona, Spain. nrodriguez@imas.imim.es
Background:
The elective treatment for noninvasive breast carcinoma has not yet been established. As a result of mammographic screening programs, the incidence of noninvasive tumors has increased and has lead to the same controversy already present had with invasive carcinomas: mastectomy or conserving therapy.
Methods:
Since 1990, 101 patients with noninvasive breast cancer were treated with irradiation following breast-conserving surgery. All the patients had irradiation of the whole breast (mean dose, 47.6 +/- 1.2 Gy). The radiation dose boost to the tumor bed was delivered in 28.7% of the cases (mean dose, 21.03 +/- 3.06 Gy), and in 71.3%, the boost was not administered.
Results:
With a median follow-up of 34 months, survival is 100%. The disease-free survival at 5 years by the Kaplan-Meier method is 93.6 +/- 8.65.
Conclusions:
The conserving treatment is a valid option for treatment of patients with ductal carcinoma in situ.
