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Updated: Aug 24, 2026
Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
Impact of tobacco smoking on platelet function in apheresis products in vitro
D Scheinichen1, H-G Heuft, C Renken
1Department of Anaesthesiology, Hannover Medical School, Hannover, Germany. scheinichen.dirk@mh-hannover.de
Background And Objectives:
The aim of this study was to analyse the platelet function, over a 5-day time-period, of apheresis-derived platelet concentrates obtained from smokers and non-smokers.
Materials And Methods:
Smoker and non-smoker plateletpheresis products were investigated on days 1, 3 and 5 of storage. Receptor expression (as evaluated by flow cytometry) and the platelet aggregation response were measured.
Results:
There was only a slight loss of platelet function in apheresis products from smokers compared to non-smokers.
Conclusions:
Smoking does not significantly change the quality of platelet preparations. The current practice, of not to exclude smokers from platelet donation, can be continued.
